Protein tools: structure prediction, blast, multiple sequence alignment, randomize sequence. Nucleic tools: Primer design. Programs for analysis and manipulation of nucleic acid and protein sequence. Includes dot plot similarity matrix, inverse, complement, double-stranded conversions. Examines DNA sequence to find large, non-overlapping open reading frames (ORFs) and sites for all restriction enzymes that cut the sequence just once. Tool to visualize sequence alignments and consensus sequences showing the relative frequencies of the bases at each position. Generates and annotates plasmid maps using only plasmid DNA sequence as input. Figures may be rendered in PNG, JPG, SVG or SVGZ format. Alignments for multiple protein sequences or structures using information from sequence database searches, secondary structure prediction, available homologs with 3D structures. Analyzes a DNA sequence to identify Restriction Enzyme Sites and generate a comprehensive map overview of their locations within the DNA sequence. Conversion of sequences to FASTA format. Primer selection. Restriction maps. Translations. Reverse complement and reverse nucleotide sequences. Program for faster alignment of short oligonucleotides onto reference sequences for next generation sequencing data analysis. Online visualisation of comparisons between up to five prokaryotic genome sequences, using Artemis Comparison Tool (ACT). Source.