Typically, boundaries of breast tumors in U.S. image volumes are even more poorly defined after the onset of chemotherapy.19 An assumption in this study was that the only tissues to change in the chemotherapy were those of the tumor and the boundaries of the tumor. The automated estimation of tumor volume of the later scan involved these steps: All U.S. system settings were identical between studies on the same individual since Doppler signals are very sensitive to system settings. Color Doppler artifacts were removed and the overlap regions in corresponding color vessel segments in the two registered image volumes were identified and cropped. Three methods were identified for independent validation of B-mode image volume registration using the Doppler image volume: We are experimenting with display styles that make it easier to read articles in PMC. Our first effort uses eBook readers, which have several 'ease of reading' features already built in. These PMC articles are best viewed in the iBooks reader. You may notice problems with the display of certain parts of an article in other eReaders. Source.